Novel benzofuran derivatives with dual 5-HT 1A receptor and serotonin transporter affinity

AM Venkatesan, O Dos Santos, J Ellingboe…

Index: Venkatesan, Aranapakam M.; Dos Santos; Ellingboe, John; Evrard, Deborah A.; Harrison, Boyd L.; Smith, Deborah L.; Scerni, Rosemary; Hornby, Geoffrey A.; Schechter, Lee E.; Andree, Terrence H. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 824 - 827

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Citation Number: 20

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Several benzofuran derivatives linked to a 3-indoletetrahydropyridine through an alkyl chain were prepared and evaluated for serotonin transporter and 5-HT 1A receptor affinities. Their design, synthesis and structure–activity relationships are described. ... Previous reports from our ...

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