Cholesterol Functionalized Aliphatic N-Substituted 8-Membered Cyclic Carbonate

Shrinivas Venkataraman, Kenneth Mineart, Vivek Prabhu, James Hedrick, Yi-Yan Yang

Index: 10.1039/C8PY00406D

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Abstract

Straightforward synthesis of cholesterol functionalized aliphatic N-substituted 8 membered cyclic carbonate (Chol-8m) monomer is reported. Well-defined poly(ethylene glycol) (PEG) diblock copolymers were readily accessed via organo catalytic ring opening polymerization. These polymers show promise as building blocks for self-assembled nanostructures and steric stabilizers for liposomes.