Oxidation Reactions of Azines. 10. Synthesis, Structure, and Oxodihydroxylation of 3-Hydroxymethyl-1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine

AT Soldatenkov, AV Temesgen, KB Polyanskii…

Index: Soldatenkov; Temesgen; Polyanskii; Soldatova; Kolyadina; Golovtsov; Sergeeva Chemistry of Heterocyclic Compounds, 2003 , vol. 39, # 4 p. 471 - 477

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Abstract

Abstract It has been established that oxidation of a mixture of 1-methyl-4-phenyl-1, 2, 3, 6- tetrahydropyridine and dicyanomethane or formaldehyde with manganese dioxide gives 3- hydroxymethyl-1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine, the structure of which was confirmed by X-ray structural analysis. Some oxidative conversions by potassium permanganate of the product formed and its esters have been studied. These included ...