Synthetic Communications

Zinc (0)-mediated formation of carbon-carbon bond from γ-bromo crotonate

F Orsini, F Pelizzoni, G Ricca

Index: Orsini, F.; Pelizzoni, F.; Ricca, G. Synthetic Communications, 1982 , vol. 12, # 14 p. 1147 - 1154

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Citation Number: 15

Abstract

Abstract The coupling reaction of allylic halides with dif f ferent organometallic reagents has been widely util i zed for synthetic purpose. 1 Unfortunately, with the exception of primary halides which give mostly α attack and of hindered substrates which prefer γ at tack, the lack of regioselectivity is a great hand i cap for the generalization of the method.