Russian Chemical Bulletin

Base-catalyzed intramolecular heterocyclization of o-alkynylbenzhydrazides

TF Mikhailovskaya, SF Vasilevsky

Index: Mikhailovskaya; Vasilevsky Russian Chemical Bulletin, 2010 , vol. 59, # 3 p. 632 - 636

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Citation Number: 3

Abstract

Abstract The reaction of methyl o-(2-R-ethynyl) benzoates with hydrazine affords either fused 4-R-methylphthalazin-1-ones or 2-amino-3-R-methylideneisoindolin-1-ones. The latter are on treatment with KOH undergo recyclization into the corresponding 4-R-