Tetrahedron letters
First total synthesis of (−)-α-conidendrin
P Boissin, R Dhal, E Brown
Index: Boissin, Patrick; Dhal, Robert; Brown, Eric Tetrahedron Letters, 1989 , vol. 30, # 33 p. 4371 - 4374
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Citation Number: 15
Abstract
Abstract Regioselective introduction of a benzoxy group, in the benzylic position of the β- benzyl-γ-butyrolactone (R)-(+)-8, was achieved by tretment with NBS followed with benzyl alcohol. α-Alkylation of the lithium enolate of the resulting intermediate 11, with Full-size image (< 1 K)