Migratory Decarboxylative Coupling of Coumarins: Synthetic and Mechanistic Aspects

R Jana, JJ Partridge, JA Tunge

Index: Jana, Ranjan; Partridge, James J.; Tunge, Jon A. Angewandte Chemie - International Edition, 2011 , vol. 50, # 22 p. 5157 - 5161

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Citation Number: 32

Abstract

Construction of new CÀC bonds by decarboxylative coupling is a powerful synthetic method since it avoids highly basic reaction conditions and preformed organometallic reagents that produce stoichiometric metal waste.[1] In addition, the byproduct (CO2) is nontoxic and requires no special separation procedures. Thus several research groups have demonstrated that decarboxylative couplings are practical alternatives to standard cross- ...