Tetrahedron letters

Synthesis of guanine 7-oxide, an antitumor antibiotic from Streptomyces species

F Nohara, M Nishii, K Ogawa, K Isono, M Ubukata…

Index: Nohara, Fujio; Nishii, Masahiro; Ogawa, Kazuo; Isono, Kiyoshi; Ubukata, Makoto; et. al Tetrahedron Letters, 1987 , vol. 28, # 12 p. 1287 - 1290

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Citation Number: 20

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The first synthesis of the antitumor antibiotic guanine 7-oxide (VI) has been achieved via a 4-step route starting from phenacyl bromide (I) and the nitropyrimidone III and proceeding through the intermediates IVe and Ve. ... Satisfactory spectral data and/or elemental analyses ...