Synthesis of bridged 1, 4-diazepane derivatives via Schmidt reactions

…, OO Grygorenko, PK Mykhailiuk, DM Volochnyuk…

Index: Mityuk, Andrey P.; Denisenko, Aleksandr V.; Dacenko, Oleksandr P.; Grygorenko, Oleksandr O.; Mykhailiuk, Pavel K.; Volochnyuk, Dmitriy M.; Tolmachev, Andrey A. Tetrahedron Letters, 2010 , vol. 51, # 13 p. 1790 - 1792

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Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A series of bridged 1,4-diazepanes (ie, diazabicyclo[n.3.2]alkanes, n = 3–5) selectively protected at one of the nitrogen atoms was prepared, for possible application in drug design, via Schmidt rearrangement of the corresponding ketones. ... Aliphatic diamines exemplify privileged structures ...