Wittig reactions in water media employing stabilized ylides with aldehydes. Synthesis of α, β-unsaturated esters from mixing aldehydes, α-bromoesters, and Ph3P in …
A El-Batta, C Jiang, W Zhao, R Anness…
Index: Shen, Yanchang; Xin, Yuankang; Zhao, Jianhua Tetrahedron Letters, 1988 , vol. 29, # 47 p. 6119 - 6120
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Citation Number: 138
Abstract
Water is demonstrated to be an effective medium for the Wittig reaction over a wide range of stabilized ylides and aldehydes. Despite sometimes poor solubility of the reactants, good chemical yields normally ranging from 80 to 98% and high E-selectivities (up to 99%) are
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