Stereoselective Synthesis of Phosphoryl??Substituted Phenols

…, Y Liu, Y Zhou, C Zhao, M Goto, SF Yin…

Index: Xiong, Biquan; Li, Mei; Liu, Yanxi; Zhou, Yongbo; Zhao, Changqiu; Goto, Midori; Yin, Shuang-Feng; Han, Li-Biao Advanced Synthesis and Catalysis, 2014 , vol. 356, # 4 p. 781 - 794

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Citation Number: 11

Abstract

Abstract: Copper-catalyzed CÀX activation-phosphorylation of aryls bearing different groups has been achieved using P (O) ÀH compounds as efficient phosphorylation reagents without the assistance of any ligand. Optically active H-phosphinates can also act as good substrates in the reaction, giving the (Sp)-phosphoryl substituted phenolic compounds stereospecifically with retention of configuration at the phosphorus center. Furthermore, it ...