The ortho-substituted N, N-diacetylaniline as a selective acetylating reagent
Y Murakami, K Kondo, K Miki, Y Akiyama, T Watanabe…
Index: Murakami, Yasuoki; Kondo, Kazuhiro; Miki, Kazuki; Akiyama, Yoko; Watanabe, Toshiko; Yokoyama, Yuusaku Tetrahedron Letters, 1997 , vol. 38, # 21 p. 3751 - 3754
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Citation Number: 36
Abstract
Selective acetylation of the less hindered amino group in the presence of the more hindered amino group with the use of 2-trifluoromethyl-N, N-diacetylaniline 2c is described. This acetylation with 2c yielded the corresponding less hindered monoacetamide exclusively, simply, conveniently, and in good yields.
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