Preparation of Organoaluminum Reagents from Propargylic Bromides and Aluminum Activated by PbCl2 and Their Regio??and Diastereoselective Addition to …
…, H Gao, P Mayer, P Knochel
Index: Guo, Li-Na; Gao, Hongjun; Mayer, Peter; Knochel, Paul Chemistry - A European Journal, 2010 , vol. 16, # 32 p. 9829 - 9834
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Citation Number: 27
Abstract
Abstract Various propargylic and allenic aluminum reagents have been easily prepared by a direct insertion of aluminum into propargylic bromides in the presence of PbCl 2 (1 mol%). These organoaluminum reagents react with carbonyl compounds to afford the corresponding allenic alcohols or homopropargylic alcohols in good to excellent yields with high regio-and diastereoselectivity.
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