Novel KCNQ2/Q3 agonists as potential therapeutics for epilepsy and neuropathic pain

PC Fritch, G McNaughton-Smith…

Index: Zhu, Lei; Zhang, Mingbao Journal of Organic Chemistry, 2004 , vol. 69, # 21 p. 7371 - 7374

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Citation Number: 32

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. ... 3a−j.(23-27) Further alkylation of 3a−j with methyl trifluoromethanesulfonate afforded triflate salts, which were then treated with adamantane-1- carboxylic acid hydrazide to afford adamantyl derivatives 4a−j.(28) Alkylation of 2 ...