Determination of labetalol hydrochloride in drug formulations by spectrophotometry
N Rahman, H Rahman…
Index: Rahman, Nafisur; Rahman, Habibur; Azmi, Syed Najmul Hejaz Journal of the Chinese Chemical Society, 2007 , vol. 54, # 1 p. 185 - 196
Full Text: HTML
Citation Number: 13
Abstract
Abstract A validated, selective and sensitive spectrophotometric method has been developed for the determination of labetalol hydrochloride in commercial dosage forms. The method is based on the coupling reaction of positive diazonium ion of 4- aminobenzenesulfonic acid with phenolate ion of labetalol to form a colored azo compound which absorbs maximally at 395 nm. Under the optimized experimental conditions, the ...
Related Articles:
Studies on the photostability and in vitro phototoxicity of Labetalol
[Andrisano, Vincenza; Ballardini, Roberto; Hrelia, Patrizia; Cameli, Norma; Tosti, Antonella; Gotti, Roberto; Cavrini, Vanni European Journal of Pharmaceutical Sciences, 2001 , vol. 12, # 4 p. 495 - 504]