Synthesis and study of anti-inflammatory activity of some novel cyclophane amides

…, AMA Rasheed, AI Rabia, D Chamundeeswari

Index: Rajakumar, Perumal; Mohammed Abdul Rasheed; Iman Rabia; Chamundeeswari Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6019 - 6023

Full Text: HTML

Citation Number: 20

Abstract

Synthesis of new supramolecules architecturally novel and of potential importance in the context of designing simple models for studying biomolecular interactions stimulates the imaginative skill of synthetic chemists. The basic crown ether has been modified by substituting the oxygen donor atom by sulfur and/or nitrogen atom and introducing functional groups, viz., amide, ester in the ring to use them as models of protein–metal binding sites in biological systems, 1 ...