Synthese einiger Thioxanthen??Derivate

O Schindler, H Lehner, W Michaelis…

Index: Schindler,O. et al. Helvetica Chimica Acta, 1963 , vol. 46, p. 1097 - 1108

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Citation Number: 3

Abstract

Abstract The synthesis of some thioxanthene derivatives as possible metabolites of Methixerc (VI-hydrochloride) is described. The VON BRAUN degradation of VI with cyanogen bromide leads to the demethyl derivative 9-[(3-piperidyl)-methyl]-thioxanthene (VIII). Oxidation of Methixen with hydrogen peroxide at 20 gives a mixture of the two steroisomerie sulfoxides IX and X; they were separated by preparative paper- ...