Facile trisulphide formation in the thermolysis of N, N′-diacetyl-L-cystine bismethylamide, an excellent model for protein-bound cystine

M Ghadimi, RR Hill

Index: Ghadimi, Moharam; Hill, Roger R. Journal of the Chemical Society, Chemical Communications, 1991 , # 13 p. 903 - 904

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Citation Number: 11

Abstract

The thermolysis of N, N′-diacetyl-L-cystine bismethylamide not only displays the known chemistry of protein-bound cystine, but also draws attention to the facile formation of trisulphides and, when conducted under alkaline conditions, allows the isolation of the simplest α, β-dehydropeptide.