Sequential catalytic process: synthesis of quinoline derivatives by AuCl 3/CuBr-catalyzed three-component reaction of aldehydes, amines, and alkynes
F Xiao, Y Chen, Y Liu, J Wang
Index: Xiao, Fengping; Chen, Yulin; Liu, Yu; Wang, Jianbo Tetrahedron, 2008 , vol. 64, # 12 p. 2755 - 2761
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Citation Number: 116
Abstract
A sequential catalytic process has been developed based on gold-catalyzed nucleophilic addition of terminal alkynes to imines, and gold-catalyzed intramolecular reaction of aromatic ring to alkynes. This one-pot reaction of aldehydes, amines, and alkynes gives quinoline derivatives in good yields.
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