Tetrahedron letters

Organometallic reactions in aqueous media with indium

CJ Li, TH Chan

Index: Li, C. J.; Chan, T. H. Tetrahedron Letters, 1991 , vol. 32, # 48 p. 7017 - 7020

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Citation Number: 275

Abstract

Abstract Allylation reactions of aldehydes and ketones occurred smoothly with indium metal in aqueous media. Compared to similar reactions with zinc and tin, the reaction with indium proceeds without the need of any promoter. The reaction can be extended to the synthesis of 2-methylene-γ-lactone 6 via the condensation of carbonyl compounds with 2- bromomethylacrylate 4.

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