Ring-closure reactions. 21. Intramolecular. beta.-elimination competing with ring formation from o-(. omega.-bromoalkoxy) phenoxides over a wide range of ring sizes

A Dalla Cort, L Mandolini, B Masci

Index: Cort, Antonella Dalla; Mandolini, Luigi; Masci, Bernardo Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 3979 - 3982

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Citation Number: 3

Abstract

Results The reactions were carried out in 99% Me2S0 at 25.0" C. In all cases the initial concentration of 1 was 0.5 mM, ie, low enough to ensure the intramolecular course of the reaction. Two sets of experiments were carried out. In one set, the anion was generated by the addition of a stoichiometric amount of KOH to the parent phenol, so that the reaction was run in the virtual absence of OH-. In the other, a 2-fold quantity of base was added. GLC ...