Reaction of nitric oxide with amines

T Itoh, K Nagata, Y Matsuya, M Miyazaki…

Index: Itoh, Takashi; Nagata, Kazuhiro; Matsuya, Yuji; Miyazaki, Michiko; Ohsawa, Akio Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3582 - 3585

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Citation Number: 124

Abstract

Reactions of nitric oxide (NO) with amines in organic solvents were studied using Hantzsch dihydropyridines and aromatic primary amines as substrates. Hantzsch dihydropyridines are readily oxidized by nitric oxide to give the corresponding pyridines in quantitative yields. The addition of oxygen accelerates the reaction rate considerably. On the other hand, aromatic primary amines give deaminated products by the reaction with nitric oxide only in the ...