Silica-supported silver as a green and sustainable catalyst for [3+2] cycloaddition reaction of azomethine ylides with 2'-hydroxychalcone derivatives

Suchithra Madhavan, Sentaro Okamoto

Index: 10.1002/cctc.201702035

Full Text: HTML

Abstract

A reusable heterogeneous silver nanoparticle catalyst supported on silica was used for the [3+2] cycloaddition reaction of azomethine ylides with 2'-hydroxychalcone derivatives. The green and sustainable catalytic protocol afforded highly functionalized pyrrolidines, indolizidines, and pyrrolizidines in good yields with high regio and diastereoselectivities.