Preparation, X-ray structure and propylaminolysis of 7, 7-dichloro-5, 7-dihydro-thieno [3, 4-b] pyridin-5-one

…, B Staskun, MA Fernandes

Index: Van Es, Theodorus; Staskun, Benjamin; Fernandes, Manuel A. Journal of Chemical Research, 2007 , # 6 p. 373 - 376

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Abstract

Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (≊ 50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo [3, 4-b] pyridine derivatives.