New synthesis of isoquinoline alkaloids, thalifoline, corypalline, and cherylline

…, A Shiina, T Fushimi, J Katakawa, N Fujii, H Yajima

Index: Irie, Hiroshi; Shiina, Ayako; Fushimi, Tamaki; Katakawa, Jun'ichi; Fujii, Nobutaka; Yajima, Haruaki Chemistry Letters, 1980 , p. 875 - 878

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Citation Number: 24

Abstract

Isoquinoline alkaloids, thalifoline, corypalline, and cherylline, were synthesised by application of the cyclisation reaction of β-phenylethyl isocyanate to N-methylisoquinoline lactam with Magic Methyl and the regioselective cleavage reaction of aromatic methoxyl groups with methionine and methanesulphonic acid.