Selective. ALPHA.-Mono-and. ALPHA.,. ALPHA.-Dialkylations of 1, 3-Diketones Using Solid Base Prepared from Sodium Ethoxide and Alumina.
N Yoshihara, T Kitagawa, I Ihara, S Hasegawa…
Index: Yoshihara, Nobutoshi; Kitagawa, Teruhiro; Ihara, Ikuko; Hasegawa, Sadao; Hasegawa, Tadashi Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 4 p. 1185 - 1187
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Citation Number: 4
Abstract
The alkylation of 1, 3-diketones with alkyl halides using a solid base prepared from sodium ethoxide and alumina was carried out. The amount of 0.4 mol of sodium ethoxide on 50 g of alumina showed the best reactivity for alkylation. Selective mono-and dialkylation could be achieved by controlling the reaction temperature.
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