Can innate immune system targets turn up the heat on 'cold' tumours?

Asher Mullard

Index: 10.1038/nrd.2017.264

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Abstract

Can innate immune system targets turn up the heat on 'cold' tumours? Can innate immune system targets turn up the heat on 'cold' tumours?, Published online: 28 December 2018; doi:10.1038/nrd.2017.264STING, RIG-I and NLRP3 agonists might increase the effectiveness of immuno-oncology checkpoint inhibitors, while antagonists of these targets offer an anti-inflammatory bonus.