N-Alkenyl nitrone dipolar cycloaddition routes to piperidines and indolizidines. Part 8. The scope of tandem reactions involving hydroxylamine-alkyne cyclisations
EC Davison, IT Forbes, AB Holmes, JA Warner
Index: Davison, Edwin C.; Forbes, Ian T.; Holmes, Andrew B.; Warner, Jacqueline A. Tetrahedron, 1996 , vol. 52, # 35 p. 11601 - 11624
Full Text: HTML
Citation Number: 34
Abstract
A tandem sequence of hydroxylamine-alkyne cyclisation/1, 3-dipolar cycloaddition, provides useful entry into tricyclic systems of type 4. The scope of such reactions is explored in this paper. A novel cascade cyclisation of N-hydroxypyrrolidines of type 26 and 28 involving hydroxylamine-alkyne cyclisation, Cope elimination and 1, 3-dipolar cycloaddition is also reported.
Related Articles:
[Nishimoto, Yoshihiro; Kajioka, Masayuki; Saito, Takahiro; Yasuda, Makoto; Baba, Akio Chemical Communications, 2008 , # 47 p. 6396 - 6398]
Pd-catalyzed cycloisomerization to 1, 2-dialkylidenecycloalkanes. 1
[Trost, Barry M.; Tanoury, Gerald J.; Lautens, Mark; Chan, Chuen; MacPherson, David T. Journal of the American Chemical Society, 1994 , vol. 116, # 10 p. 4255 - 4267]
Polyacetylenverbindungen, 203. Zur Biogenese des Matricariaesters
[Bohlmann,F.; Burkhardt,T. Chemische Berichte, 1972 , vol. 105, p. 521 - 528]