Cleavage of carbon-carbon bonds with high stereochemical control. 7. Chiral. alpha.-silyl benzoylcycloalkanes undergo base-catalyzed cleavage with retention of …

LA Paquette, GD Maynard, CS Ra…

Index: Paquette, Leo A.; Maynard, George D.; Ra, Choon Sup; Hoppe, Manfred Journal of Organic Chemistry, 1989 , vol. 54, # 6 p. 1408 - 1418

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Citation Number: 16

Abstract

Results An Optically Active Cyclopentyl Substrate. A structural property especially suited to assessing the stereochemical course of cleavage reactions is optical activity. Implementation of this probe does require, however, that the absolute configurations of the starting material and product be known without question. Beyond that, we wished not to introduce steric compression near the reaction site as a possible source of complication ...