A cobalt-catalyzed steroid synthesis

RL Funk, KPC Vollhardt

Index: Funk; Vollhardt Journal of the American Chemical Society, 1977 , vol. 99, # 16 p. 5483 - 5484

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Citation Number: 90

Abstract

Sir: The steroid nucleus has been the target of numerous, often ingenious, synthetic schemes.] We recently reported the co- balt-catalyzed one-step synthesis of tricyclic ring systems B via cooligomerization of diynes A with bis(trimethylsily1) acetylene (BTMSA) in the presence of C ~ CO ( CO ) ~ ~ ... I). In this reaction five new carbon-carbon bonds are formed with control of stereochemistry to result in what one might envisage to constitute the ABC-ring portion ...