Synthesis of Substituted Azepino [3, 4??b] indole??1, 5??diones
J Perron, B Joseph, JY Mérour
Index: Perron, Julien; Joseph, Benoit; Merour, Jean-Yves European Journal of Organic Chemistry, 2004 , # 22 p. 4606 - 4613
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Citation Number: 4
Abstract
Abstract Cyclic β-amino esters 4, obtained from lactams, were condensed with indole-2- carbonyl chloride to afford the corresponding amides. Similarly, unusual conditions led to cyclisation at the 3-position of the indole moiety in the presence of pTSA and ethylene glycol to afford previously unknown pentacyclic derivatives 12 and 15.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
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