1-Acyl-3-cyclooctylguanidines

J Sluka, F Šmejkal, Z Buděšínský

Index: Sluka, Jaroslav; Smejkal, Frantisek; Budesinsky, Zdenek Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 5 p. 1595 - 1600

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Citation Number: 2

Abstract

Abstract On recation of cyclooctylamine with the sulfate of S-methylisothiourea cyclooctylguanidine was formed which was acylated with the methyl esters of 5-halogeno- and 3, 5-dihalogeno-2-alkoxybenzoic acids. The 1-acyl-3-cyclooctylguanidine I-XVII formed were tested for their antiviral effect against the influenza virus A/NWS, A-PR8 and A 2 Singapore, and further against the viruses NDV, herpes 2, vaccinia and WEE. In the in ...