Bis-ammonium salts. Derivatives of fluorene, carbazole and phenothiazine

CJ Cavallito, AP Gray, EE Spinner

Index: Cavallito et al. Journal of the American Chemical Society, 1954 , vol. 76, p. 1862,1865

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Citation Number: 26

Abstract

R and R 'is benzhydryl, 9-fluorenyl, 2-fluorenyl, 9-fiuorenylethyl, 9-carbazylethyl, or 10- phenothiazinylethyl has been prepared. Quaternization of bis-(dialky1amino)-alkanes with benzhydryl bromide and 9-bromofluorene proceeded in excellent yield provided that solvolytic conditions were avoided. The compounds have been examined for neuromuscular blocking action, and several found to possess considerable activity. In particular, the bis-9- ...