Tetrahedron

Ligand-free Ag (I)-catalyzed carboxylative coupling of terminal alkynes, chloride compounds, and CO 2

X Zhang, WZ Zhang, LL Shi, C Zhu, JL Jiang, XB Lu

Index: Zhang, Xiao; Zhang, Wen-Zhen; Shi, Ling-Long; Zhu, Chuang; Jiang, Jiao-Lai; Lu, Xiao-Bing Tetrahedron, 2012 , vol. 68, # 44 p. 9085 - 9089

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Citation Number: 19

Abstract

Simple silver (I) slats were found to be highly efficient and selective catalyst for carboxylative coupling of aryl-or alkyl-substituted terminal alkynes, CO2, and various allylic, propargylic or benzylic chlorides to exclusively yield functionalized 2-alkynoates. The activity is about 300 times that of the previously reported N-heterocyclic carbene copper (I) catalytic system. The ligand-free silver (I) catalytic system showed the wide generality of substrates involving ...

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