Kinetic resolutions of chiral unsaturated alcohols that cannot be resolved efficiently via enantioselective epoxidation

K Burgess, LD Jennings

Index: Burgess, Kevin; Jennings, Lee D. Journal of the American Chemical Society, 1990 , vol. 112, # 20 p. 7434 - 7435

Full Text: HTML

Citation Number: 56

Abstract

I1 those resolutions indicate that enantioselectivity is high when the substituent R1 is relatively small, and, for such substrates, the R enantiomer is acylated faster than its S antipode. Subsequently, it occurred to us that the only restriction on these resolutions might be that the alcohol must have one small and (6)(a) Burgess, K.; Henderson, 1. Tetrahedron Asymmetry 1990, 1, 57.(b) Burgess, K.; Jennings, LJ Org. Chem. 1990, 55, 1138.