Tetrahedron Letters

A mild oxidation method of hydroxamic acids: efficient trapping of acyl nitroso intermediates

S Iwasa, K Tajima, S Tsushima, H Nishiyama

Index: Iwasa, Seiji; Tajima, Kentaro; Tsushima, Shinji; Nishiyama, Hisao Tetrahedron Letters, 2001 , vol. 42, # 34 p. 5897 - 5899

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Citation Number: 56

Abstract

Nitroso intermediates play an important role in organic chemistry since highly functionalized molecules such as pyrrolidines, amino alcohols and aza sugars are easily available from nitroso compounds by hetero Diels–Alder reaction. 1 The prominent utility of nitroso intermediate is that the synthesis of 1,4-amino alcohols as building blocks for total synthesis of natural products. 2 Although recent studies on the synthesis of 1,4-amino alcohols are still focused and ...