Ruthenium-catalyzed S-propargylation of thiols enables the rapid synthesis of propargylic sulfides

…, K Wada, Y Morisaki, T Mitsudo

Index: Kondo, Teruyuki; Morisaki, Yasuhiro; Uenoyama, Shin-Ya; Wada, Kenji; Mitsudo, Take-Aki Journal of the American Chemical Society, 1999 , vol. 121, # 37 p. 8657 - 8658

Full Text: HTML

Citation Number: 41

Abstract

A new and highly efficient catalytic system based on CpRuClL2 is proposed for the S- propargylation of thiols by propargylic carbonates under neutral conditions, in which specific requirements inherent to the different reactivities of aliphatic and aromatic thiols are achieved by tuning both the nature of the ancillary ligand L and the experimental conditions.

Related Articles:

Cyanuric chloride as promoter for the oxidation of sulfides and deoxygenation of sulfoxides

[Bahrami, Kiumars; Khodaei, Mohammad M.; Sohrabnezhad, Samira Tetrahedron Letters, 2011 , vol. 52, # 48 p. 6420 - 6423]

Alkynes as masked ylides: gold-catalysed intermolecular reactions of propargylic carboxylates with sulfides

[Davies, Paul W.; Albrecht, Sebastien J.-C. Chemical Communications, 2008 , # 2 p. 238 - 240]

Bimetallic system for the synthesis of diorganyl selenides and sulfides, chiral β-seleno amines, and seleno-and thioesters

[Gul, Kashif; Narayanaperumal, Senthil; Dornelles, Luciano; Rodrigues, Oscar E.D.; Braga, Antonio Luiz Tetrahedron Letters, 2011 , vol. 52, # 28 p. 3592 - 3596]

Zn in ionic liquid: an efficient reaction media for the synthesis of diorganyl chalcogenides and chalcogenoesters

[Narayanaperumal, Senthil; Alberto, Eduardo E.; Gul, Kashif; Kawasoko, Cristiane Yuriko; Dornelles, Luciano; Rodrigues, Oscar E.D.; Braga, Antonio Luiz Tetrahedron, 2011 , vol. 67, # 25 p. 4723 - 4730]

A “tag-and-modify” approach to site-selective protein modification

[Lin, Yuya A.; Chalker, Justin M.; Floyd, Nicola; Bernardes, Goncalo J. L.; Davis, Benjamin G. Journal of the American Chemical Society, 2008 , vol. 130, # 30 p. 9642 - 9643]

More Articles...