An alternative method for the selective bromination of alkylbenzenes using NaBrO3/NaHSO3 reagent

D Kikuchi, S Sakaguchi, Y Ishii

Index: Kikuchi, Daisuke; Sakaguchi, Satoshi; Ishii, Yasutaka Journal of Organic Chemistry, 1998 , vol. 63, # 17 p. 6023 - 6026

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Citation Number: 105

Abstract

R-Brominated alkylbenzenes are a valuable class of compounds in organic synthesis, since they are frequently used as the starting materials for synthesis of a wide variety of important compounds. R-Bromination of alkylbenzenes is usually performed by the use of bromine, 1 NBS, 2 CBrCl3, 3 CuBr2, 4 and Br-/CAN5 under heating or irradiation of light. To achieve the bromination by these reagents in satisfactory yields, the reaction must be carried out in ...