Direction of cyclization of 1, 2-bis (cyanomethyl) benzenes

AS Dey, A Rosowsky, EJ Modest

Index: Dey; Rosowsky; Modest The Journal of organic chemistry, 1970 , vol. 35, # 2 p. 536 - 539

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Citation Number: 4

Abstract

2-Amino-3-cyano-lH-indenes bearing a single chlorine substituent on the benzene ring were required as synthetic intermediates. lb A convenient route to amino nitriles of this type is the base-catalyzed Thorpe cyclization of 1, 2-bis (cyanornethyl) benzenes, which has been