Acutiphycin and 20, 21-didehydroacutiphycin, new antineoplastic agents from the cyanophyte Oscillatoria acutissima
JJ Barchi Jr, RE Moore…
Index: Barchi,J.J.; Moore,R.E.; Patterson,G.M. Journal of the American Chemical Society, 1984 , vol. 106, p. 8193
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Citation Number: 100
Abstract
Abstract: The lipophilic extract of the freshwater blue-green alga Oscillatoria acutissima contains two novel macrolides, acutiphycin (1) and 20, 21-didehydroacutiphycin (2), which exhibit cytotoxicity and antineoplastic activity. The structures and absolute stereochemistries of 1 and 2 have been determined by spectral studies and chemical degradation.
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