Chemical and Pharmaceutical Bulletin

Studies on Seven-membered Ring Compounds. XXXVI. Synthesis of Azulene Derivatives by Ring Closure of β-Cycloheptatrienyl-substituted Carbonyl Compounds

T WATANABE, N SOMA

Index: Watanabe,T.; Somo,N. Chemical and Pharmaceutical Bulletin, 1971 , vol. 19, p. 2215 - 2221

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Citation Number: 14

Abstract

Treatment of 2-phenyl-3-(2, 4, 6-cycloheptatrien-1-yl) propionaldehyde ethylene acetal (III) with stannic chloride in benzene followed by dehydrogenation with sulfur afforded 2- phenylazulene (V) and 1-(2-hydroxyethyloxy)-2-phenylazulene (VI). Benz [a] azulene (XV) was obtained along with anthracene (XVI) when 2-(2, 4, 6-cycloheptatrien-1-yl)- benzaldehyde (XII) or its ethylene acetal (XI) was treated with stannic chloride in benzene ...

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