Naphthomoles. 7. Synthesis of 4, 11-dimethoxynaphtho [2, 3-f] indole-5, 10-dione and 4-methoxynaphtho [2, 3-f]-indole-5, 10-dione

AE Shchekotikhin, VN Buyanov, KF Turchin…

Index: Shchekotikhin; Buyanov; Turchin; Baberkina; Avramenko; Suvorov Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 8 p. 902 - 906

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Citation Number: 8

Abstract

Many compounds of the anthraquinone series are widely used as antitu~rnor agents. Adrianycin, discovered in 1969 [2], is one of the most effective medicinal preparations, acting against various forms of tumor with a moderate toxicity. The 4- demethoxy analog of rubomycin, assigned the name "carminomycin," was isolated from Actinornadura carmdnata in 1973 by GF Gauze and is also widely used as an antitumor preparation [3]. On the ...