Effective, selective hydroalkoxylation/cyclization of alkynyl and allenyl alcohols mediated by lanthanide catalysts

X Yu, SY Seo, TJ Marks

Index: Yu, Xianghua; Seo, SungYong; Marks, Tobin J. Journal of the American Chemical Society, 2007 , vol. 129, # 23 p. 7244 - 7245

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Citation Number: 102

Abstract

Catalytic hydroalkoxylation/cyclization reactions of alkynyl and allenyl alcohols are efficiently mediated by homoleptic lanthanide amides Ln [N (SiMe3) 2] 3 (Ln= La, Nd, Sm, Y, and Lu). Conversions are found to be highly selective with products distinctly different from those produced by conventional transition metal catalysts. Turnover frequencies as high as 18.0 h- 1 at 60° C are observed. Kinetic studies indicate that these transformations are zero-order ...

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