Preparation and Double Michael Addition Reactions of a Synthetic Equivalent of the Nazarov Reagent
M Amat, F Arioli, M Pérez, E Molins, J Bosch
Index: Amat, Mercedes; Arioli, Federica; Perez, Maria; Molins, Elies; Bosch, Joan Organic Letters, 2013 , vol. 15, # 10 p. 2470 - 2473
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Citation Number: 6
Abstract
A synthetic equivalent of the Nazarov reagent, the silyl derivative 2, able to undergo base- catalyzed double Michael addition reactions with α, β-unsaturated carbonyl compounds has been developed. The new reagent satisfactorily reacts with unsaturated indolo [2, 3-a] quinolizidine lactams to give pentacyclic yohimbinone-type derivatives.
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