Antiinflammatory activity of 5, 6-diaryl-2, 3-dihydroimidazo [2, 1-b] thiazoles. Isomeric 4-pyridyl and 4-substituted-phenyl derivatives
…, KA Razgaitis, BM Sutton, MJ DiMartino…
Index: Lantos, I.; Bender, P. E.; Razgaitis, K. A.; Sutton, B. M.; DiMartino, M. J.; et al. Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 72 - 75
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Citation Number: 73
Abstract
a Tested at 50 mg/kg, PO.* Tested at 25 mg/kg, PO. Active 1 out of 3 times tested. p= 0.05, as judged by Student's t test. ep= 0.01, as judged by Student's t test. fp= 0.001, as judged by Student's t test. g NS= not significant; p> 0.05, as judged by Student's t test. and to incorporate 4-pyridyl substituents into the series. Chemistry. Unsymmetrically substituted imidazo-[2,141 thiazoles (6a, b) were prepared regioselectively by condensation of ...
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