Tetrahedron letters

An efficient method for hydrolysis of N-monosubstituted amides via acetoxypivalimides

T Tsunoda, O Sasaki, S Itô

Index: Tsunoda, Tetsuto; Sasaki, Osamu; Ito, Sho Tetrahedron Letters, 1990 , vol. 31, # 5 p. 731 - 734

Full Text: HTML

Citation Number: 9

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Various N-monosubstituted carboxamides were efficiently hydrolyzed in two steps through acetoxypivalimides. The method can he applied to a wide range of amides without racemization of α-position of the acyl groups. The amines can also be recovered.

Related Articles:

Formation of nitrosamines by alkylation of diazotates

[Cooper, Curt S.; Peyton, Albert L.; Weinkam, Robert J. Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4116 - 4119]

A Tunable Route for the Synthesis of Azomethine Imines and β-Aminocarbonyl Compounds from Alkenes

[Magnus, Philip; Garizi, Negar; Seibert, Kimberly A.; Ornholt, Alexandra Organic Letters, 2009 , vol. 11, # 24 p. 5646 - 5648]

Catalytic activity of MCM-41–TBD in the selective preparation of carbamates and unsymmetrical alkyl carbonates from diethyl carbonate

[Carloni, Silvia; De Vos, Dirk E.; Jacobs, Pierre A.; Maggi, Raimondo; Sartori, Giovanni; Sartorio, Raffaella Journal of Catalysis, 2002 , vol. 205, # 1 p. 199 - 204]

Amberlyst??15 in Ionic Liquid: An Efficient and Recyclable Reagent for Nucleophilic Substitution of Alcohols and Hydroamination of Alkenes

[Qureshi, Ziyauddin S.; Deshmukh, Krishna M.; Tambade, Pawan J.; Dhake, Kishor P.; Bhanage, Bhalchandra M. European Journal of Organic Chemistry, 2010 , # 32 p. 6233 - 6238]

Amberlyst??15 in Ionic Liquid: An Efficient and Recyclable Reagent for Nucleophilic Substitution of Alcohols and Hydroamination of Alkenes

[Qureshi, Ziyauddin S.; Deshmukh, Krishna M.; Tambade, Pawan J.; Dhake, Kishor P.; Bhanage, Bhalchandra M. European Journal of Organic Chemistry, 2010 , # 32 p. 6233 - 6238]

More Articles...