Multilevel selectivity in the mild and high-yielding chlorosilane-induced cleavage of carbamates to isocyanates

PY Chong, SZ Janicki, PA Petillo

Index: Chong, Pek Y.; Janicki, Slawomir Z.; Petillo, Peter A. Journal of Organic Chemistry, 1998 , vol. 63, # 23 p. 8515 - 8521

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Citation Number: 63

Abstract

The silane-induced cleavage of a series of Np-tolylcarbamates and N-phenethylcarbamates to isocyanates has been investigated as a function of chlorosilane, carbamate substituent, and reaction conditions. Reaction yields were determined from the isolated ureas, which were formed by trapping the corresponding isocyanates with isobutylamine. Under room- temperature conditions, multilevel selectivity in carbamate activation has been ...