Model studies towards paecilomycine A–C: exploring scaffold diversity through a key intramolecular Pauson–Khand reaction

G Mehta, R Samineni, P Srihari

Index: Mehta, Goverdhan; Samineni, Ramesh; Srihari, Pabbaraja Tetrahedron Letters, 2011 , vol. 52, # 14 p. 1663 - 1666

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Citation Number: 11

Abstract

Neurodegenerative disorders (Alzheimer's, Huntington's and Parkinson's diseases) are characterized by a net loss of neurons and neuronal connectivity from specific regions of the central nervous system (CNS) and constitute a major public health concern particularly in the context of the aging world population. , , and While natural neurotrophins like nerve growth factor (NGF), neurotrophins (NT-3,4,5) and brain derived neurotrophic factor (BDNF) embodying polypeptidyl ...