SH-methylation of SH-containing heterocycles with dimethyl carbonate via phase-transfer catalytic reaction
…, J Quan, SB Li, Y Zheng, LM Zhu
Index: Xie, Jian-Gang; Quan, Jing; Li, Shu-Bai; Zheng, Yan; Zhu, Li-Min Synthetic Communications, 2011 , vol. 41, # 6 p. 871 - 878
Full Text: HTML
Citation Number: 7
Abstract
Abstract A reaction of SH-containing heterocycles with dimethyl carbonate (DMC) in the presence of K2CO3 and tetrabutylammonium bromide (Bu4NBr) gave heteroaryl methyl thioethers in 44–93% yields. The reaction was carried out under mild conditions. This method provided a useful synthetic method for preparation of various heteroaryl methyl thioethers without the use of toxic methylic halides or dimethyl sulfate.
Related Articles:
Easy access to silicon (0) and silicon (II) compounds
[Alawode, Olajide E.; Robinson, Colette; Rayat, Sundeep Journal of Organic Chemistry, 2011 , vol. 76, # 1 p. 216 - 222]