… of P450 BM??3 and an NADP+ Cofactor Recycling System: Towards a Technical Application of Heme??Containing Monooxygenases in Fine Chemical Synthesis
…, H Schulze, RD Schmid, V Urlacher
Index: Maurer, Steffen C.; Schulze, Holger; Schmid, Rolf D.; Urlacher, Vlada Advanced Synthesis and Catalysis, 2003 , vol. 345, # 6-7 p. 802 - 810
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Citation Number: 126
Abstract
Abstract: Cytochrome P450 monooxygenases are potentially a very useful class of hydroxylation catalysts; they are able to introduce oxygen at activated and non-activated carbon-hydrogen bonds and thus lead to regio-and/or stereochemically pure compounds. However, this potential is lowered by their intrinsic low activity and inherent instability. P450- catalysed biotransformations require a constant supply of NAD (P) H, making the process ...
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